PLAS Research Solutions
What is PLAS
We present a first-in-class commercial solution for the laser synthesis of nanoparticles, specifically ultra-pure, biocompatible nanoparticles, with automated in-line control. Our compact PLAS Research Solutions platform is designed for National Universities, Biotechnology Research Centers, Pharmaceutical Companies, and Research Laboratories.
Our product effectively addresses the limitations of the current environment by bringing nanoparticle manufacturing directly to the end user. The absence of ligands and impurities simplifies preclinical evaluation and standardizes characterization and validation.
Why is PLAS
Laser synthesis of nanoparticles does not require precursors, salts, ligands, surfactants, or toxic reducing agents. This method ensures reproducibility and compatibility with biomedical research and manufacturing. Additionally, it eliminates the need for high pressures, high temperatures, high voltages, strong magnetic fields, or deep vacuum—thus requiring no specialized equipment, cleanrooms, or trained personnel. The laser synthesis process is a one-step method that removes the necessity for filtration, chemical purification, drying, packaging, re-sterilization, transportation, and other post-processing steps. This significantly enhances production speed, drastically minimizes the risk of chemical and biological contamination, and reduces both capital and operating costs for production lines. We present first-in-class commercial solutions for the laser synthesis of ultra-pure, biocompatible nanoparticles, featuring automated in-line control. Our compact laser synthesis platform, known as PLAS Research Solutions, is designed for National Universities, Biotechnology Research Centers, Pharmaceutical Companies, and Research Laboratories.
How PLAS works
Pulsed Laser Ablation in Solution (PLAS) is a laser synthesis of nanoparticles that relies on the physical principle of material evaporation and plasma formation from a target immersed in a solution under laser irradiation. The evaporated material and plasma condense in the solution, agglomerating into biocompatible nanoparticles and forming a colloidal suspension. The solution can be any liquid that is transparent to the laser wavelength, including water, alcohols, and specialized buffers. A target is placed in a sterile cartridge or a sterile flow reactor filled with solution. The laser beam scans and evaporates the target, while another monochromatic laser beam periodically passes through the cartridge, tuned to the absorption wavelength of the target material. As this beam passes through the solution, its energy is absorbed, and the degree of attenuation indicates concentration. Built-in Dynamic Light Scattering (DLS) and Spectrometry modules measure the concentration and automatically stop ablation once the desired level of biocompatible nanoparticles is achieved, showcasing the effectiveness of PLAS Research Solutions.
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